PGT-M - Japan

PGT-M
Benefits
Indications

What is PGT-M test?

PGT-M (formerly PGD) is an early genetic diagnosis of an IVF prior to its transfer to the uterus.

By analyzing DNA from each embryo, normal embryos can be preferentially selected to be transferred into the woman’s uterus.

What is the procedure?

Why should use PGT-M test?

Higher chance of a healthy baby: It maximises the chances of having a baby free from the disease for couples who have a high genetic risk.
Possibility of PGT-M+PGT-A: We can perform PGT-M and PGT-A for screening of aneuploidies in the same biopsy.
We can perform PGT-M for most monogenic disorders.

Download full disease list

Who should use PGT-M test?

This type of PGT-M is indicated for couples with personal or familial high-risk for single gene conditions including Cystic Fibrosis, Fragile-X syndrome, Muscular dystrophy, Huntington’s disease, and others.

Download full disease list

Test limitations

Limitations of PGT-M can arise from the IVF treatment itself. For example, poor ovarian stimulation can reduce the chance that an unaffected embryo will be identified since PGT-M success is linked to the number of high-quality embryos produced in the cycle.
PGT-M is only available if a genetic mutation(s) causative a specific disease has been identified. PGT-M cannot be offered if the genetic cause is not known.
PGT-M provides no guarantee of a completely healthy baby.
Finally, in some countries there can be legal limitations. The laws regulating PGT-M depends on the country and in some countries, its use is prohibited or tightly regulated and requires, for some indications, a case-by-case authorization by a National Committee.

Documentation

PGT-M Specialists' documents

Technical Sheets

Download

Brochure

Download

Scientific evidence

Relevant related studies:

G. Kakourou et al., The clinical utility of PGD with HLA matching a collaborative multi-centre ESHRE study. Human Reproduction, Vol.33, No.3 pp. 520–530. Fertility and Sterility

M De Rycke, et al., ESHRE PGD Consortium data collection XIV–XV: cycles from January 2011 to December 2012 with pregnancy follow-up to October 2013, Human Reproduction, Volume 32, Issue 10, October 2017, Pages 1974–1994.

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We work to make a world in which infertility is no longer an impossible barrier. Together with clinics and fertility doctors worldwide we investigate human reproduction to change the lives of couples who are trying to conceive.

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What is PGT-M test?

What is the procedure?

Why should use PGT-M test?

Who should use PGT-M test?

Test limitations

Technical Sheets

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Relevant related studies:

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PGT-M+PGT-A can be run simultaneously

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Are you interested?

Learn about genetics

What is PGT-M test?

What is the procedure?

Why should use PGT-M test?

Who should use PGT-M test?

Test limitations

Technical Sheets

Brochure

Relevant related studies:

Can we help you?

Igenomix and fertility

Learn about genetics

NEW COURSES AVAILABLE:

Non Invasive PGS, Maria Vera

Other services you may be interested

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