ALICE is a test that detects pathogenic bacteria and recommends adequate treatment.
Pathogenic bacteria cause chronic endometritis, which is linked to implantation failure and recurrent miscarriage.
In cases of repeated implantation failure or recurrent pregnancy loss, chronic endometritis can rise to 66%.
Human Microbiome Project Consortium. Structure, function and diversity of the healthy human microbiome. Nature 2012; 486:207–14.
Moreno I, Codoñer FM, Vilella F, Valbuena D, Martinez-Blanch JF, Jimenez-Almazan J, Alonso R, Alama P, Remohi J, Pellicer A, Ramon D, Simon C. Evidence that the endometrial microbiota has an effect on implantation success or failure. Am J Obstet Gynecol. 2016; 215:684-703.
Moreno I, Cicinelli E, Garcia-Grau I, Gonzalez M, Bau D, Vilella F, De Ziegler D, Resta L, Valbuena D, Simon C. The diagnosis of chronic endometritis in infertile asymptomatic women: a comparative study of histology, microbial cultures, hysteroscopy, and molecular microbiology. Am J Obstet Gynecol. 2018, DOI: 10.1016/j.ajog.2018.02.012.
着床不全を防ぐために女性の子宮内膜の
着床能の状態を評価します
子宮内の菌を調べるだけでなく、
細菌叢のバランスを評価する検査です
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