CGT: Carrier Genetic Test

Why use CGT test?

• It is a clinically validated genetic screening test based on Next-Generation Sequencing (NGS).

• Our different CGT options, tailored to each patient’s needs, make it the most complete test available. 

What CGT test options are available?

CGT 600

Analyzes by massive sequencing 6,600 pathogenic mutations and 547 genes linked to more than 600 genetic disorders. It is the most complete panel currently available.

• Being tested by such a complete panel guarantees maximum efficiency of gamete bank.
• CGT Match included.
• Delivery of results 15 business days.

CGT 250

Panel which includes analysis by massive sequencing (NGS) of 250 genes and 3,500 mutations associated to with the most prevalent diseases.

• Applying the 250 panel to a gamete bank guarantees its eciency because this means it is genetically tested.
• It avoids incompatible donations which could result in children being born with a genetic disorder.
• CGT Match included.
• Delivery of results: 15 business days.

CGT ONE

Recommended in cases where the person has a family history and believes they carry a mutation in a specific gene. CGT One uses NGS to sequence the entire gene or a panel of genes linked to the disease in order to locate the existing mutations.

• Analysis of the gene requested by the patient.
• Delivery of results: 15 business days.

Who should use CGT test?

• For any couple who wants to form a family to know the risk of transmitting hereditary disorders to their children.
• Patients before an assisted reproduction treatment.
• Patients before a treatment with donor sperm or eggs.

Test limitations

• The sensitivity of the test is 98%.
• We only analyze genes on the list available at www.cgt.igenomix.com, reporting results based on knowledge current at the time of testing. Therefore, only genes included in this list will be detected.
• The sensitivity of the test is 98%.
• The method is based on analysis by massive parallel sequencing and bioinformatics, studying all the exons of the genes included on our gene list. This includes adjacent intronic regions before or after position +5 and -5. Variants located outside the gene regions studied, such as gene-expression regulatory regions or intronic regions before or after position +5 and -5 are not detected.
• No inversions, deletions, or duplications over 20 nucleotides long that are not referred to in the list available at www.cgt.igenomix.com are studied.
• Germ mosaics (mutations only present in gametes) are not detected by this analysis because the DNA material studied is obtained from a blood sample.
• A negative result for the genes indicated does not exclude the possibility that a de novo mutation may appear in the offspring.